Treatments
Treatment
Polynucleotides
elasticity, and overall radiance
(small bumps up to 48 hours)
Polynucleotides, widely known as the ‘salmon injectable facial’, use purified salmon DNA to boost skin regeneration, hydration, and repair for smoother, healthier, more radiant skin.
What Are Polynucleotides?
Polynucleotides are bio stimulating injectable gels derived from highly purified DNA fragments. They work by improving skin regeneration, hydration, and elasticity while reducing inflammation and oxidative stress.
They do not add volume like filler, instead, they improve overall skin quality, making them ideal for clients seeking natural, subtle rejuvenation.
How Do Polynucleotides Work?
Once injected, polynucleotides:
- Promote fibroblast activity
- Boost collagen and elastin production
- Improve hydration by increasing the skin’s water-binding ability
- Support tissue repair and healing
- Reduce inflammation and redness
- Improve cellular turnover
This results in healthier, brighter, firmer-looking skin over a course of treatments.
Who Is This Treatment For?
Polynucleotides may be suitable if you would like to:
- Improve fine lines and crepey skin
- Brighten dull or tired-looking skin
- Enhance under-eye quality
- Improve elasticity and firmness
- Support skin recovery and repair
- Reduce inflammation or redness
- Achieve natural, subtle rejuvenation without volume
Areas We Treat with Polynucleotides
- Under-eye area
- Full face
- Neck
- Décolletage
- Hands
- Acne-prone or inflammatory areas
- Crepey or dehydrated skin zones
Polynucleotides Vs. Skin Boosters
Understanding the difference
| Feature | Skin Boosters | Polynucleotides |
|---|---|---|
| Main Purpose | Deep hydration and improved skin quality | Skin regeneration and repair |
| Key Ingredients | Hyaluronic acid combined with amino acids, vitamins, and antioxidants (product dependent) | Purified DNA fragments (often referred to as the ‘salmon injectable facial’) |
| How They Work | Hydrate the skin from within and improve smoothness and glow | Stimulate collagen, elastin, and cellular repair |
| Effect on Volume | No added volume | No added volume |
| Results Timeline | Visible hydration and glow within weeks | Gradual improvement over several weeks |
| Longevity | Around 6 months | 6–12 months |
| Best For | Dull, dehydrated, or uneven skin | Ageing, tired, crepey, or damaged skin |
| Common Areas Treated | Face, neck, décolletage, hands | Under-eyes, face, neck, décolletage |
| Treatment Course | Usually 3 sessions and maintenance every 6 months | Usually 3 sessions and maintenance every 6–12 months |
| Downtime | Minimal | Minimal |
What to Expect During Your Treatment
Consultation
Your practitioner will assess your skin concerns, discuss your goals, review your medical history, and design a personalised treatment plan. You will also be advised on how many sessions you may need for optimal results.
Treatment Process
1. Preparation
The skin is cleansed and numbing cream can be applied for comfort.
2. Injection Technique
Polynucleotides are gently injected using micro-needle points or a cannula, depending on the area and desired result.
3. Final Check
Your practitioner will ensure even distribution and provide aftercare guidance.
Comfort
Treatment is generally well tolerated with mild discomfort.
Recommended Course
Most clients benefit from 3 sessions, spaced 2–4 weeks apart.
Pre-Treatment Care
To ensure optimal results, please:
• Avoid alcohol for 24 hours before treatment
• Avoid ibuprofen or aspirin if possible (unless prescribed)
• Arrive with clean skin (no makeup)
• Postpone treatment if you are unwell
• Inform your practitioner of all medications and recent treatments
• Not suitable during pregnancy or breastfeeding
Post-Treatment Care
For the first 4–6 hours:
• Avoid touching, rubbing, or applying pressure to the treated area
• Avoid makeup for 4 hours
• Keep the area clean and avoid unnecessary handling
For the first 24 hours:
• Avoid strenuous exercise
• Avoid saunas, steam rooms, and hot yoga
Additional guidance:
• Small bumps or swelling are normal and usually settle within 24–48 hours
• Avoid facials, peels, or intense skincare for 1 week
Important
Possible Side Effects
Temporary effects may include:
- Redness
- Swelling
- Small bumps at injection sites
- Mild tenderness
These usually resolve quickly.
Quality
Product Quality & Safety
At Huderma, we use only premium polynucleotide products known for their safety, purity, and regenerative effectiveness.
Cost
Pricing
Polynucleotides start from £300 per session.
Multi-session packages available depending on your treatment plan.
Full pricing is available on our Pricing page.
Book a Consultation
If you’re looking to improve skin quality, hydration and natural regeneration, book a consultation with HuDerma to discuss polynucleotide treatment and whether it’s right for you